Tantisattamo Ekamol, Bello Erlaine F, Acoba Jared D
Department of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Hawaii J Med Public Health. 2012 Aug;71(8):212-7.
Nodular sclerosing Hodgkin's lymphoma commonly presents with a mediastinal mass, but it rarely compresses or invades mediastinal structures or the anterior chest wall. Histologically, it can cause necrotizing granulomatous inflammation. A woman with a right breast mass extending from an asymptomatic large mediastinal mass selectively compressing the trachea is presented. A computed tomography-guided core needle biopsy from the anterior chest wall mass revealed necrotizing granulomatous inflammation. Finally, the diagnosis of nodular sclerosing Hodgkin's lymphoma was made by incisional biopsy. Clinical suspicion of nodular sclerosing Hodgkin's lymphoma is crucial since an adequate tissue diagnosis is needed when the initial less invasive diagnostic testing is inconclusive.
结节硬化型霍奇金淋巴瘤通常表现为纵隔肿块，但很少压迫或侵犯纵隔结构或前胸壁。组织学上，它可引起坏死性肉芽肿性炎症。本文报道了一名女性患者，其右乳肿块起源于无症状的巨大纵隔肿块，该纵隔肿块选择性压迫气管。经计算机断层扫描引导下从前胸壁肿块进行的粗针活检显示为坏死性肉芽肿性炎症。最后，通过切开活检确诊为结节硬化型霍奇金淋巴瘤。临床怀疑结节硬化型霍奇金淋巴瘤至关重要，因为当初次侵入性较小的诊断性检查结果不明确时，需要进行充分的组织诊断。
