Roth-Schechter B F, Mandel P
C R Acad Hebd Seances Acad Sci D. 1975 Feb 3;280(5):629-32.
In cultivated astroblasts of hamster, clone NN, increasing concentrations of sodium pentobarbital induce morphological changes in the sense of a cell differentiation. At the same time occurs a progressive dependence on the barbiturate, illustrated by cell degeneration when the effector is eliminated from the medium containing the cultivated cells.
在仓鼠培养的成星形细胞克隆NN中,戊巴比妥钠浓度的增加会诱导细胞发生分化意义上的形态变化。与此同时,细胞对巴比妥酸盐产生了逐渐增强的依赖性,当从含有培养细胞的培养基中去除效应物时,细胞会发生退化,这就说明了这种依赖性。