[Effect of immunostimulation by Corynebacterium parvum on evolution and metastatic dissemination of Lewis's tumor in mouse C57BL/6 mice].

Treatment with Corynebacterium parvum (C. parvum) produces a significant prolongation of survival time of Lewis tumor bearing animals and reduces strikingly the incidence of pulmonary metastasis in syngeneic C57Bl/6 mice. On the other hand, treatment with Imuran, a known immunodepressive agent, reduces survival time and facilitates metastatic dissemination in the same model.