Campbell W W, Crim M C, Dallal G E, Young V R, Evans W J
Human Physiology Laboratory, US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA.
Am J Clin Nutr. 1994 Oct;60(4):501-9. doi: 10.1093/ajcn/60.4.501.
Dietary protein requirements of elderly people were determined by short-term nitrogen-balance techniques and using calculations recommended by the 1985 Joint FAO/WHO/UNU Expert Consultation. Twelve men and women aged 56-80 y were randomly assigned to groups that consumed either 0.80 +/- 0.01 or 1.62 +/- 0.02 g protein.kg-1.d-1 (mean +/- SEM). Net nitrogen balance was negative for the lower-protein group (-4.6 +/- 3.4 mg N.kg-1.d-1) and positive for the higher-protein group (13.6 +/- 1.0 mg N.kg-1.d-1); the intake required for nitrogen equilibrium was estimated to be 1.00 g.kg-1.d-1. Nitrogen-balance data from three previous protein requirement studies in elderly people were recalculated by using the same balance formula and combined with the current study data to provide an overall weighted mean protein requirement estimate of 0.91 +/- 0.043 g.kg-1.d-1. Together, the current and retrospective nitrogen-balance data suggest that the mean protein requirement in elderly adults is considerably greater than the 0.60 g.kg-1.d-1 established by the 1985 Joint FAO/WHO/UNU Expert Consultation. A safe protein intake for elderly adults would be 1.0-1.25 g.kg-1.d-1 of high-quality protein.
老年人的膳食蛋白质需求量是通过短期氮平衡技术并采用1985年粮农组织/世界卫生组织/联合国大学联合专家磋商会推荐的计算方法来确定的。12名年龄在56 - 80岁的男性和女性被随机分为两组，分别摄入0.80±0.01或1.62±0.02克蛋白质·千克⁻¹·天⁻¹（均值±标准误）。低蛋白组的净氮平衡为负（-4.6±3.4毫克氮·千克⁻¹·天⁻¹），高蛋白组为正（13.6±1.0毫克氮·千克⁻¹·天⁻¹）；氮平衡所需的摄入量估计为1.00克·千克⁻¹·天⁻¹。利用相同的平衡公式重新计算了此前三项关于老年人蛋白质需求量研究的氮平衡数据，并与当前研究数据相结合，得出总体加权平均蛋白质需求量估计值为0.91±0.043克·千克⁻¹·天⁻¹。当前和回顾性的氮平衡数据共同表明，老年人的平均蛋白质需求量远高于1985年粮农组织/世界卫生组织/联合国大学联合专家磋商会确定的0.60克·千克⁻¹·天⁻¹。老年人安全的蛋白质摄入量应为1.0 - 1.25克·千克⁻¹·天⁻¹的优质蛋白质。
