Buatti J M, Harari P M, Leigh B R, Cassady J R
Department of Radiation Oncology, University of Florida Health Science Center, Gainesville 32610-0385.
Am J Clin Oncol. 1994 Oct;17(5):444-7. doi: 10.1097/00000421-199410000-00018.
Angiosarcoma is a rare, highly malignant soft tissue sarcoma that sometimes occurs in the breast as a late sequela of treatment for breast cancer. The conventional treatment for radiation-induced angiosarcoma is surgery, which is associated with a poor overall prognosis. We report a case of radiation-induced angiosarcoma of the intact breast that occurred 6 years after breast conservation therapy. Simple mastectomy was performed; however, rapid chest wall recurrence of angiosarcoma ensued. After salvage therapy with combined radiotherapy and hyperthermia, the patient has been disease-free for more than 3 years.
血管肉瘤是一种罕见的、高度恶性的软组织肉瘤，有时作为乳腺癌治疗的晚期后遗症出现在乳腺中。放射诱导性血管肉瘤的传统治疗方法是手术，但总体预后较差。我们报告一例保乳治疗6年后发生在完整乳腺的放射诱导性血管肉瘤病例。患者接受了单纯乳房切除术；然而，血管肉瘤随后迅速在胸壁复发。在联合放疗和热疗的挽救性治疗后，患者已无病生存超过3年。
