Merino E, Hellín D, Amorós L M, Pernas J, Jiménez-Cervantes J
Servicio de O.R.L., Hospital Universitario Virgen de la Arrixaca, Muŕcia.
An Otorrinolaringol Ibero Am. 1994;21(4):357-68.
Between the years 1971 and 1984, 428 patients with the diagnosis of laryngeal carcinoma were operated at the ENT Department of Virgen de la Arrixaca Hospital (Murcia, Spain). All of them submited to laryngectomy. The 5-years actuarial recurrence-free rate and its correlations with host factor are studied. That is to say: staging, histology of the primary lesion, incidence of lymph node metastasis and the treatment done. The overall 5-years actuarial recurrence free rate was 74 percent. The hard drinkers had a significative lower survival rate (53 percent) that no drinkers (81 percent). Glottic localization had better survival rate (83 percent) than supraglottic (68 percent). Both stages I and II had a survival rate of 87 percent. 70 percent stage III and only 41 percent the stage IV. Squamous cell carcinoma with good differentiation had a significative better prognosis (79 percent) in well differentiated and 58 percent when the differentiation were poor. Patients with metastasis in lymph nodes had lower survival rate (49 percent) than those without metastases (83 percent).
1971年至1984年间,428例被诊断为喉癌的患者在西班牙穆尔西亚市阿瑞萨卡圣母医院耳鼻喉科接受了手术。他们均接受了喉切除术。研究了5年精算无复发生存率及其与宿主因素的相关性。也就是说:分期、原发灶组织学、淋巴结转移发生率以及所进行的治疗。总体5年精算无复发生存率为74%。酗酒者的生存率(53%)显著低于不饮酒者(81%)。声门区定位的生存率(83%)高于声门上区(68%)。I期和II期的生存率均为87%。III期为70%,IV期仅为41%。高分化鳞状细胞癌的预后明显较好(79%),分化差时为58%。有淋巴结转移的患者生存率(49%)低于无转移的患者(83%)。