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红细胞增多症和血液稀释对新生儿循环的影响。

Effects of polycythaemia and haemodilution on circulation in neonates.

作者信息

Mandelbaum V H, Guajardo C D, Nelle M, Linderkamp O

机构信息

Department of Neonatology Paediatrics, University of Heidelberg, Germany.

出版信息

Arch Dis Child Fetal Neonatal Ed. 1994 Jul;71(1):F53-4. doi: 10.1136/fn.71.1.f53.

Abstract

Haemodilution in nine neonates resulted in significant mean (SEM) decrease of packed cell volume (0.67 (0.01) to 0.55 (0.01)) and increases in cardiac output (250 (16) to 308 (25) ml/min/kg) and blood flow velocities of the internal carotid artery and the coeliac artery (+20%). However, red cell flows in the aorta, carotid and coeliac arteries did not change during haemodilution, thereby indicating that haemodilution did not improve oxygen transport.

摘要

对9名新生儿进行血液稀释后,血细胞比容显著降低(平均值(标准误)从0.67(0.01)降至0.55(0.01)),心输出量增加(从250(16)增至308(25)ml/min/kg),颈内动脉和腹腔动脉的血流速度增加(+20%)。然而,在血液稀释过程中,主动脉、颈动脉和腹腔动脉中的红细胞流量并未改变,因此表明血液稀释并未改善氧输送。

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