Mandelbaum V H, Guajardo C D, Nelle M, Linderkamp O
Department of Neonatology Paediatrics, University of Heidelberg, Germany.
Arch Dis Child Fetal Neonatal Ed. 1994 Jul;71(1):F53-4. doi: 10.1136/fn.71.1.f53.
Haemodilution in nine neonates resulted in significant mean (SEM) decrease of packed cell volume (0.67 (0.01) to 0.55 (0.01)) and increases in cardiac output (250 (16) to 308 (25) ml/min/kg) and blood flow velocities of the internal carotid artery and the coeliac artery (+20%). However, red cell flows in the aorta, carotid and coeliac arteries did not change during haemodilution, thereby indicating that haemodilution did not improve oxygen transport.
对9名新生儿进行血液稀释后,血细胞比容显著降低(平均值(标准误)从0.67(0.01)降至0.55(0.01)),心输出量增加(从250(16)增至308(25)ml/min/kg),颈内动脉和腹腔动脉的血流速度增加(+20%)。然而,在血液稀释过程中,主动脉、颈动脉和腹腔动脉中的红细胞流量并未改变,因此表明血液稀释并未改善氧输送。