Zuckerman H, Kahana A, Carmel S
Gynecol Invest. 1975;6(5):265-71. doi: 10.1159/000301522.
The antimicrobial property of human uterine cervical mucus was tested in three groups of women. Healthy women, using no contraception, women using an intrauterine device and women receiving hormonal treatment for contraception. Cervical mucus was taken on the 10th, 14th, 18th and 22nd day of the menstrual cycle. Cervical mucus had a strong inhibitory effect on the growth of Micrococcus lysodeicticus in all three groups. The strength of the inhibitory effect on the other microorganisms were in the following order: Staphylococcus albus, Staphylococcus aureus, Proteus mirabilis, Escherichia coli, Candida albicans, Streptococcus haemolyticus, Streptococcus faecalis. Use of an intrauterine device did not affect the antimicrobial effect of cervical mucus. The use of hormonal contraceptive canceled the antimicrobial effect on the series of microorganisms, with the exception of M. lysodeicticus. The maximum inhibitory effect occurred on the 14th day and declined toward the end of the menstrual cycle.
在三组女性中测试了人子宫颈黏液的抗菌特性。分别为未使用避孕措施的健康女性、使用宫内节育器的女性以及接受激素避孕治疗的女性。在月经周期的第10天、14天、18天和22天采集宫颈黏液。在所有三组中,宫颈黏液对溶菌微球菌的生长均有强烈抑制作用。对其他微生物的抑制作用强度依次为:白色葡萄球菌、金黄色葡萄球菌、奇异变形杆菌、大肠杆菌、白色念珠菌、溶血性链球菌、粪肠球菌。使用宫内节育器不影响宫颈黏液的抗菌效果。激素避孕的使用消除了对一系列微生物的抗菌效果,但对溶菌微球菌除外。最大抑制作用出现在第14天,并在月经周期结束时下降。