Christensen J T, Boldsen J, Westergaard J G
Department of Obstetrics and Gynecology, Odense University Hospital, Denmark.
Acta Obstet Gynecol Scand. 1997 Sep;76(8):784-9. doi: 10.3109/00016349709024348.
The aim of this study was to determine the ovarian volume by transvaginal ultrasonography in a gynecologically healthy population of women using no contraception, using intrauterine contraceptive device, or using oral contraceptive.
The study had a cross-sectional design. The ovaries of 428 women aged 1445 who contacted the family planning clinic in the county of Funen were examined. Most of the statistical analyses were carried out using standard techniques. However polynominal regression analysis was used to model ovarian volumes as a function of the day of cycle.
No differences between the volumes of the right and the left ovary were found in any of the groups. Significant differences were found between the ovarian volumes of the three groups. The ovarian volumes were found to be largest in women using intrauterine contraceptive device, lesser in women using no contraception and smallest in women using oral contraception. A significant difference was found of the ovarian volumes throughout the menstrual cycle in women who were not using oral contraception. The ovarian volumes did not change throughout the menstrual cycle in women using oral contraception. In women not using oral contraception the largest ovary increased in volume from the start of the cycle to day 19, thereafter the volume declined. No evidence of any change of volume over the menstrual cycle was found in the smallest ovary and, for women using oral contraception, both ovaries. There was no correlation between age, height, weight, parity, and ovarian volume in any of the groups.
The ovarian volumes, in gynecologically healthy women using intrauterine contraceptive device, are larger than in women using no contraception. It appears that oral contraception reduces the volumes of both ovaries in all phases of the menstrual cycle to equal levels.
本研究旨在通过经阴道超声检查确定未采取避孕措施、使用宫内节育器或口服避孕药的妇科健康女性群体的卵巢体积。
本研究采用横断面设计。对428名年龄在14至45岁之间、前往富宁县城计划生育诊所就诊的女性的卵巢进行了检查。大多数统计分析采用标准技术。然而，多项式回归分析被用于将卵巢体积建模为月经周期天数的函数。
在任何一组中，左右卵巢体积均未发现差异。三组的卵巢体积之间存在显著差异。发现使用宫内节育器的女性卵巢体积最大，未采取避孕措施的女性次之，口服避孕药的女性最小。在未使用口服避孕药的女性中，整个月经周期的卵巢体积存在显著差异。使用口服避孕药的女性在整个月经周期中卵巢体积没有变化。在未使用口服避孕药的女性中，最大的卵巢体积从周期开始到第19天增加，此后体积下降。在最小的卵巢以及使用口服避孕药的女性的两个卵巢中，未发现月经周期中体积有任何变化的证据。在任何一组中，年龄、身高、体重、产次与卵巢体积之间均无相关性。
使用宫内节育器的妇科健康女性的卵巢体积大于未采取避孕措施的女性。口服避孕药似乎在月经周期的所有阶段都将两个卵巢的体积减小到相等水平。
