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影响小鼠腹腔细胞对猪蛔虫黏附反应的体液因素。

Humoral factors affecting mouse peritoneal cell adherence reactions to Ascaris suum.

作者信息

Ziprin R, Jeska E L

出版信息

Infect Immun. 1975 Sep;12(3):499-504. doi: 10.1128/iai.12.3.499-504.1975.

DOI:10.1128/iai.12.3.499-504.1975
PMID:809354
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC415315/
Abstract

The abilities of normal mouse peritoneal exudate cells and fluids to mediate in vitro cell adherence reactions to Ascaris suum juveniles were investigated. Exudates were induced by intraperitoneal injection of Sephadex G-25 or by infection with A. suum and changes in the peritoneal cell populations were determined. The presence of a heat-labile component, probably complement, and a heat-stable component, probably immunoglobulin, in the peritoneal exudate fluid were required for optimum in vitro cell adherence reactions. The in vitro cell adherence reactions were inhibited by ethylenediaminetetraacetic acid; the inhibition was overcome by the addition of calcium and magnesium ions.

摘要

研究了正常小鼠腹腔渗出细胞和液体介导体外对猪蛔虫幼虫细胞黏附反应的能力。通过腹腔注射葡聚糖凝胶G - 25或感染猪蛔虫诱导渗出液，并确定腹腔细胞群体的变化。腹腔渗出液中存在一种可能是补体的热不稳定成分和一种可能是免疫球蛋白的热稳定成分，是体外细胞黏附反应达到最佳状态所必需的。体外细胞黏附反应受到乙二胺四乙酸的抑制；添加钙和镁离子可克服这种抑制作用。

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本文引用的文献

1
Chemotoxis of mononuclear cells.单核细胞的化学毒性
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Mouse peritoneal cell reactions to parasitic nematodes. II. In vitro cell adherence.小鼠腹膜细胞对寄生线虫的反应。II. 体外细胞黏附。
J Reticuloendothel Soc. 1973 Aug;14(2):146-57.
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J Reticuloendothel Soc. 1974 Sep;16(3):150-60.
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Mouse peritoneal exudate cell reactions to parasitic worms. I. Cell adhesion reactions.小鼠腹膜渗出细胞对寄生虫的反应。I. 细胞黏附反应。
Immunology. 1969 Jun;16(6):761-71.
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Fine structure of leukocytes adhering to the cuticle of Ascaris suum larvae. I. Pyroninophils.
J Parasitol. 1969 Feb;55(1):22-31.
8
Effect of concanavalin A on phagocytosis by mouse peritoneal macrophages.伴刀豆球蛋白A对小鼠腹腔巨噬细胞吞噬作用的影响。
J Reticuloendothel Soc. 1975 Jan;17(1):10-9.
9
Specific IgE antibodies in immune adherence of normal macrophages to Schistosoma mansoni schistosomules.正常巨噬细胞与曼氏血吸虫童虫免疫黏附中的特异性IgE抗体
Nature. 1975 Feb 6;253(5491):474-5. doi: 10.1038/253474a0.

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