与免疫球蛋白V(D)J重组相关的基因在小鼠2号染色体和人类11号染色体上相连。 - Suppr

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超能文献

Genes associated with immunoglobulin V(D)J recombination are linked on mouse chromosome 2 and human chromosome 11.

作者信息

Huppi K, Siwarski D, Shaughnessy J, Klemsz M J, Shirakata M, Maki R, Sakano H

机构信息

Laboratory of Genetics, NCI/NIH, Bethesda, MD 20892.

出版信息

Immunogenetics. 1993;37(4):288-91. doi: 10.1007/BF00187456.

DOI:10.1007/BF00187456

PMID:8093609

Abstract

摘要

相似文献

Genes associated with immunoglobulin V(D)J recombination are linked on mouse chromosome 2 and human chromosome 11.与免疫球蛋白V(D)J重组相关的基因在小鼠2号染色体和人类11号染色体上相连。

Immunogenetics. 1993;37(4):288-91. doi: 10.1007/BF00187456.

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Mutational analysis of terminal deoxynucleotidyltransferase-mediated N-nucleotide addition in V(D)J recombination.V(D)J重组中末端脱氧核苷酸转移酶介导的N-核苷酸添加的突变分析。

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Intermolecular V(D)J recombination is prohibited specifically at the joining step.分子间V(D)J重组在连接步骤中被特异性禁止。

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Circular DNA resulting from recombination between V-(D)-J joining signals and switch repetitive sequences in mouse thymocytes.小鼠胸腺细胞中V-(D)-J连接信号与转换重复序列重组产生的环状DNA。

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Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes.转录因子Pax5（BSAP）可反式激活RAG介导的免疫球蛋白基因V(H)到DJ(H)的重排。

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Factors and forces controlling V(D)J recombination.控制V(D)J重组的因素和力量。

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Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.重排免疫球蛋白基因中体细胞突变的边界：5' 边界靠近启动子，3' 边界距 V(D)J 基因约 1 kb。

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The basis for the mechanistic bias for deletional over inversional V(D)J recombination.缺失型V(D)J重组相对于倒位型V(D)J重组的机制性偏好的基础。

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本文引用的文献

A severe combined immunodeficiency mutation in the mouse.小鼠中的一种严重联合免疫缺陷突变。

Nature. 1983 Feb 10;301(5900):527-30. doi: 10.1038/301527a0.

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.免疫球蛋白重链可变区基因由三段DNA片段组成：VH、D和JH。

Cell. 1980 Apr;19(4):981-92. doi: 10.1016/0092-8674(80)90089-6.

Somatic generation of antibody diversity.抗体多样性的体细胞产生。

Nature. 1983 Apr 14;302(5909):575-81. doi: 10.1038/302575a0.

Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: studies with cloned viral DNA.阿贝尔逊鼠白血病病毒基因组及同源细胞基因的结构：对克隆病毒DNA的研究

Cell. 1980 Dec;22(3):777-85. doi: 10.1016/0092-8674(80)90554-1.

Nucleotide sequence of the mouse hck gene.小鼠hck基因的核苷酸序列。

Nucleic Acids Res. 1987 Nov 25;15(22):9600. doi: 10.1093/nar/15.22.9600.

The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition.T细胞抗原受体的分子遗传学与T细胞抗原识别

Annu Rev Immunol. 1986;4:529-91. doi: 10.1146/annurev.iy.04.040186.002525.

The mouse mutation severe combined immune deficiency (scid) is on chromosome 16.小鼠突变型严重联合免疫缺陷（scid）位于第16号染色体上。

Immunogenetics. 1989;29(1):54-7. doi: 10.1007/BF02341614.

The V(D)J recombination activating gene, RAG-1.V(D)J重组激活基因，RAG-1。

Cell. 1989 Dec 22;59(6):1035-48. doi: 10.1016/0092-8674(89)90760-5.

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.RAG-1和RAG-2，协同激活V(D)J重组的相邻基因。

Science. 1990 Jun 22;248(4962):1517-23. doi: 10.1126/science.2360047.

Localization of the human oncogene SPI1 on chromosome 11, region p11.22.

Hum Genet. 1990 May;84(6):542-6. doi: 10.1007/BF00210807.

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