Martinez M L, Weiss R C
SmithKline Beecham Animal Health, Lincoln, Nebraska.
Vet Clin North Am Small Anim Pract. 1993 Jan;23(1):213-26. doi: 10.1016/s0195-5616(93)50013-x.
Genetic engineering technology is a rapidly developing field that has almost unlimited potential for the production of safer and more effective vaccines, therapeutic proteins, and more specific and sensitive diagnostic reagents. Although applications in veterinary medicine of genetically engineered products are presently limited by availability of species-specific reagents, the use of recombinant DNA products is increasing. Because of the recent discovery of FIV and the relevance of FIV as an animal model for the study of human immunodeficiency virus, feline genetic research is gaining in importance. Research using FIV as a human AIDS model ideally will yield many new species-specific feline recombinant DNA products that have important applications in feline medicine and research.
基因工程技术是一个快速发展的领域,在生产更安全、更有效的疫苗、治疗性蛋白质以及更特异、更灵敏的诊断试剂方面几乎具有无限潜力。虽然目前基因工程产品在兽医学中的应用因物种特异性试剂的可获得性而受到限制,但重组DNA产品的使用正在增加。由于最近发现了猫免疫缺陷病毒(FIV)以及FIV作为研究人类免疫缺陷病毒的动物模型的相关性,猫遗传学研究正变得越来越重要。以FIV作为人类艾滋病模型进行的研究理想情况下将产生许多新的物种特异性猫重组DNA产品,这些产品在猫医学和研究中具有重要应用。