Kingsnorth A N, Berg J D, Gray M R
University of Liverpool, Department of Surgery, Royal Liverpool University Hospital.
Ann R Coll Surg Engl. 1993 Jan;75(1):38-42.
In 30 patients a reconstructive technique was used after pylorus-preserving pancreaticoduodenectomy in which the anastomoses were constructed in the sequence: duodenojejunal, hepaticojejunal (8-10 cm distal) and finally duct-to-mucosa pancreaticojejunal to a separate Roux loop. Indications for surgery included periampullary tumours, (n = 13), carcinoma of the head of the pancreas (n = 10) and chronic pancreatitis (n = 4). No patient required prolonged (> 7 days) nasogastric intubation for primary gastroparesis in the early postoperative period. Postoperative morbidity (17% overall) delayed recovery and return of gastrointestinal function in one patient with a minor biliary leak (closed with 5 days' somatostatin treatment). Other morbidity included gastrointestinal haemorrhage (n = 1), wound infection (n = 2) and respiratory infection (n = 2). There were no pancreatic leaks. One patient died from a subhepatic abscess (mortality 3%). Retrospective investigations, at 3-18 months postoperatively, included endoscopy (normal in 20 patients, none taking anti-ulcer therapy), gastric emptying studies in the first 10 patients (no delay) and bentiromide test in 12 patients considered to have normal pancreatic remnants (all patients > 24% PABA excretion index). All patients who underwent resection for tumour returned to their preoperative weight.
在30例患者中,保留幽门的胰十二指肠切除术后采用了一种重建技术,其中吻合口按以下顺序构建:十二指肠空肠吻合、肝管空肠吻合(距空肠起始部8 - 10 cm),最后是胰管与空肠黏膜的胰管空肠吻合至单独的Roux袢。手术适应证包括壶腹周围肿瘤(n = 13)、胰头癌(n = 10)和慢性胰腺炎(n = 4)。术后早期没有患者因原发性胃轻瘫需要长时间(> 7天)的鼻胃管插管。术后总体发病率为17%,1例患者因轻微胆漏导致恢复延迟和胃肠功能恢复延迟(经5天生长抑素治疗后愈合)。其他并发症包括胃肠道出血(n = 1)、伤口感染(n = 2)和呼吸道感染(n = 2)。没有胰漏发生。1例患者死于肝下脓肿(死亡率3%)。术后3 - 18个月的回顾性调查包括内镜检查(20例患者正常,均未接受抗溃疡治疗)、前10例患者的胃排空研究(无延迟)以及对12例被认为胰腺残端正常的患者进行的苯替酪胺试验(所有患者对氨基苯甲酸排泄指数> 24%)。所有接受肿瘤切除的患者体重均恢复到术前水平。