脑脊液中的蛋白水解活性。
Proteolytic activity in CSF.
作者信息
Richards P T, Cuzner M L
出版信息
Adv Exp Med Biol. 1978;100:521-7. doi: 10.1007/978-1-4684-2514-7_38.
PMID:80950
Abstract
Proteolytic enzyme activity, present at both acid and neutral pH values, in cerebrospinal fluid, can be measured by a sensitive assay, which monitors the rate of 125I-basic protein breakdown on polyacrylamide gel electrophoresis. CSF cellular neutral proteinase and supernatant acid proteinase are increased in acute multiple sclerosis and in CNS infections.
摘要
脑脊液中在酸性和中性pH值下均存在的蛋白水解酶活性，可通过一种灵敏的检测方法来测定，该方法在聚丙烯酰胺凝胶电泳上监测125I-碱性蛋白的降解速率。急性多发性硬化症和中枢神经系统感染时，脑脊液细胞中性蛋白酶和上清液酸性蛋白酶会增加。
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