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无关个体RFLP模式匹配的概率。

Probability of matching RFLP patterns from unrelated individuals.

作者信息

Herrin G

机构信息

Division of Forensic Sciences, Georgia Bureau of Investigation, Decatur 30037-0808.

出版信息

Am J Hum Genet. 1993 Mar;52(3):491-7.

Abstract

RFLP patterns from more than 3,700 individuals, collected by several southeastern laboratories, were compared using a series of mathematical match criteria to determine the probability of randomly matching two samples from different individuals. Data from five loci (D1S7, D2S44, D4S139, D10S28, and D17S79) were compared in all possible combinations. The probability of declaring a false match under any of the match criteria decreased by at least one order of magnitude for each locus added to the comparison. No false matches were declared across four or more loci when match criteria approximately equivalent to that of forensic laboratories were used.

摘要

由几个东南部实验室收集的3700多名个体的限制性片段长度多态性(RFLP)模式,使用一系列数学匹配标准进行比较,以确定从不同个体中随机匹配两个样本的概率。对五个基因座(D1S7、D2S44、D4S139、D10S28和D17S79)的数据进行了所有可能组合的比较。对于添加到比较中的每个基因座,在任何匹配标准下宣布错误匹配的概率至少降低了一个数量级。当使用与法医实验室大致相当的匹配标准时,在四个或更多基因座上未宣布错误匹配。

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