组装一个MHC I类分子。
Putting together an MHC class I molecule.
作者信息
Bijlmakers M J, Ploegh H L
机构信息
Center for Cancer Research, Massachusetts Institute of Technology, Cambridge.
出版信息
Curr Opin Immunol. 1993 Feb;5(1):21-6. doi: 10.1016/0952-7915(93)90076-5.
PMID:8095788
Abstract
Formation of MHC class I complexes involves proper folding of the subunits, their assembly and interaction with peptides. Several proteins contributing to this process have been described, but a number of questions remain, in particular those concerning early folding steps and interactions with peptide in the course of biosynthesis.
摘要
MHC I类复合物的形成涉及亚基的正确折叠、组装以及与肽的相互作用。已有多种参与此过程的蛋白质被描述，但仍存在一些问题，尤其是那些关于生物合成过程中早期折叠步骤以及与肽相互作用的问题。
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