来自尼日利亚一家医院的耐甲氧西林金黄色葡萄球菌的基因分析。

Genetic analysis of methicillin-resistant Staphylococcus aureus from a Nigerian hospital.

作者信息

Udo E E, Grubb W B

机构信息

School of Biomedical Sciences, Curtin University of Technology, Perth, Western Australia.

出版信息

J Med Microbiol. 1993 Mar;38(3):203-8. doi: 10.1099/00222615-38-3-203.

DOI:10.1099/00222615-38-3-203

PMID:8095986

Abstract

Methicillin-resistant strains of Staphylococcus aureus isolated during 1985 and 1987 at a Nigerian hospital were compared by resistance profiles, plasmid analysis, and pulsed-field gel electrophoresis of chromosomal DNA. The results indicated that the isolates from the two periods were unrelated with regard to all three aspects. None of the isolates was similar to the classical MRSA nor to the epidemic MRSA of Australia or the UK. The MRSA isolated in 1985 had a similar plasmid to MRSA isolates from Singapore, but differed from them when compared by pulsed-field gel electrophoresis.

摘要

对1985年和1987年在一家尼日利亚医院分离出的耐甲氧西林金黄色葡萄球菌菌株，通过耐药谱、质粒分析以及染色体DNA的脉冲场凝胶电泳进行了比较。结果表明，这两个时期的分离株在所有三个方面均无关联。没有一个分离株与经典的耐甲氧西林金黄色葡萄球菌相似，也与澳大利亚或英国的流行耐甲氧西林金黄色葡萄球菌相似。1985年分离出的耐甲氧西林金黄色葡萄球菌与来自新加坡的耐甲氧西林金黄色葡萄球菌分离株具有相似的质粒，但通过脉冲场凝胶电泳比较时则有所不同。