McDonald J J, Chanduví B, Velarde G, Cama R, Díaz F, Carrillo L, Torre V, Watanabe J, Villarreal J, Ramírez-Ramos A
University of California, Davis.
Lancet. 1993 Apr 24;341(8852):1049-51. doi: 10.1016/0140-6736(93)92410-u.
Measurement of bioimpedance (BI) is a simple non-invasive technique that relies on the different conductivity of tissues to define body composition and can be easily adapted to automated monitoring. We assessed the accuracy of BI in monitoring rehydration and acute fluid fluxes in 35 Peruvian cholera patients. Patients were monitored throughout the acute phase of diarrhoea and followed up at 3 and 10 days. BI was compared with other objective measures of dehydration including packed cell volume, serum protein, and calculated fluid balance. BI rapidly detected inadequate treatment and acute fluid flux, correlating highly with intravascular hydration as measured by serum protein and packed cell volume. BI values during dehydration were significantly raised compared with 10-day convalescent values and age-matched controls (p < 0.05). We also encountered an unexpected difference in the bioelectrical response to dehydration and rehydration between sexes. We conclude that BI has uses in monitoring dehydrated patients, in oral rehydration trials, and in physiological studies.
生物阻抗（BI）测量是一种简单的非侵入性技术，它依靠组织的不同电导率来确定身体成分，并且能够轻松适应自动监测。我们评估了BI在监测35名秘鲁霍乱患者补液及急性液体通量方面的准确性。在腹泻急性期对患者进行全程监测，并在第3天和第10天进行随访。将BI与其他脱水客观指标进行比较，包括红细胞压积、血清蛋白和计算得出的液体平衡。BI能快速检测出治疗不充分及急性液体通量情况，与通过血清蛋白和红细胞压积测量的血管内水化程度高度相关。与10天恢复期数值及年龄匹配的对照组相比，脱水期间的BI值显著升高（p<0.05）。我们还发现男女在对脱水和补液的生物电反应方面存在意外差异。我们得出结论，BI可用于监测脱水患者、口服补液试验及生理学研究。
