迟发性运动障碍患者血清肌酸磷酸激酶升高。

Serum creatine phosphokinase elevations in patients with tardive dyskinesia.

作者信息

Egan M F, Dargham A A, Kirch D G, Wyatt R J

机构信息

Neuropsychiatry Branch, NIMH Neuroscience Research Center, St Elizabeth's, Washington, DC 20032.

出版信息

Br J Psychiatry. 1993 Apr;162:551-3. doi: 10.1192/bjp.162.4.551.

DOI:10.1192/bjp.162.4.551

PMID:8097656

Abstract

We describe a case of marked increases in serum creatine phosphokinase (CPK) associated with a dramatic exacerbation of tardive dyskinesia (TD). Chart review of eight additional patients with severe TD revealed three cases with mild CPK elevations. These cases suggest that TD, especially when accompanied by dystonia, may be associated with pathology of striated muscle.

摘要

我们描述了一例血清肌酸磷酸激酶（CPK）显著升高并伴有迟发性运动障碍（TD）急剧加重的病例。对另外8例严重TD患者的病历回顾显示，有3例患者CPK轻度升高。这些病例表明，TD，尤其是伴有肌张力障碍时，可能与横纹肌病变有关。