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对从埃塞俄比亚香蕉中提取的淀粉作为压制片剂的黏合剂和崩解剂的评价。

Evaluation of starch obtained from Ensete ventricosum as a binder and disintegrant for compressed tablets.

作者信息

Gebre-Mariam T, Nikolayev A S

机构信息

School of Pharmacy, Addis Ababa University, Ethiopia.

出版信息

J Pharm Pharmacol. 1993 Apr;45(4):317-20. doi: 10.1111/j.2042-7158.1993.tb05560.x.

DOI:10.1111/j.2042-7158.1993.tb05560.x
PMID:8098375
Abstract

The binding and disintegrant properties of starch obtained from Ensete ventricosum Musaceae have been evaluated. The effect of the starch on the physical properties such as crushing strength, friability and disintegration time of tablets of chloroquine phosphate, dipyrone and paracetamol was compared with tablets prepared with potato starch. The results show that enset starch can be used both as a tablet binder and disintegrant and the indication is that enset starch has a better binding ability and less disintegrating power than potato starch.

摘要

对从芭蕉科象腿蕉中提取的淀粉的黏合和崩解特性进行了评估。将该淀粉对磷酸氯喹、安乃近和扑热息痛片剂的物理性质(如抗压强度、脆碎度和崩解时间)的影响与用马铃薯淀粉制备的片剂进行了比较。结果表明,象腿蕉淀粉可同时用作片剂黏合剂和崩解剂,且表明象腿蕉淀粉比马铃薯淀粉具有更好的黏合能力和更低的崩解能力。

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