Kotzé J P
S Afr Med J. 1975 Sep 20;49(40):1651-4.
Evidence is presented showing that vitamin C had definite effects on lipid metabolism. The stress of captivity on free-living baboons causes a decrease in serum vitamin C levels and an increase in serum cholesterol levels. Increased dietary intake of vitamin C during the initial stages of captivity significantly decreases the serum cholesterol values. Dietary vitamin C stimulates the synthesis of cholesterol from 14C-labelled acetate and mevalonate in baboon liver homogenates and increases the turnover rate of the cholesterol body pool. Vitamin C inhibits baboon cardiac lipoprotein lipase activity.
有证据表明维生素C对脂质代谢有确切影响。圈养对自由生活的狒狒造成的应激会导致血清维生素C水平降低和血清胆固醇水平升高。在圈养初期增加维生素C的膳食摄入量可显著降低血清胆固醇值。膳食中的维生素C可刺激狒狒肝脏匀浆中从14C标记的乙酸盐和甲羟戊酸合成胆固醇，并提高胆固醇体内池的周转率。维生素C可抑制狒狒心脏脂蛋白脂肪酶的活性。
