Young B, Rapp R P, Perrier D, Kostenbauder H, Hackman J, Blacker H M
Surg Neurol. 1975 Sep;4(3):339-42.
An anticonvulsant regimen is described using diphenylhydantoin specifically designed for use in the acutely head injured patient. Initial doses of diphenylhydantoin based on body weight and maintenance doses determined by plasma concentrations of the drug are utilized to provide immediate and maintainable anticonvulsant blood levels.