Young B, Rapp R P, Perrier D, Kostenbauder H, Hackman J, Blacker H M
Surg Neurol. 1975 Sep;4(3):339-42.
An anticonvulsant regimen is described using diphenylhydantoin specifically designed for use in the acutely head injured patient. Initial doses of diphenylhydantoin based on body weight and maintenance doses determined by plasma concentrations of the drug are utilized to provide immediate and maintainable anticonvulsant blood levels.
描述了一种使用二苯妥英的抗惊厥方案,该方案专为急性颅脑损伤患者设计。根据体重确定二苯妥英的初始剂量,并根据药物的血浆浓度确定维持剂量,以提供即时且可维持的抗惊厥血药浓度。