Balkwill F
Imperial Cancer Research Centre, Lincoln's Inn Fields, London, UK.
Immunol Today. 1993 Apr;14(4):149-50. doi: 10.1016/0167-5699(93)90228-D.
Research into cytokines has reached a challenging stage. Their importance to physiological and pathological processes is undoubted and the clinical application of both the molecules and their antagonists is of increasing importance. Every month more novel cytokine molecules are identified, each with a perplexing multiplicity and redundancy of action. In talks that ranged from rheumatoid arthritis, oncology and lymphocyte subsets, to transcription factors and xenopus mesoderm, a recent meeting* in London discussed the latest cytokine news.
细胞因子的研究已进入一个具有挑战性的阶段。它们对生理和病理过程的重要性毋庸置疑,这些分子及其拮抗剂的临床应用正变得越来越重要。每月都有更多新的细胞因子分子被识别出来,每一种都具有令人困惑的多种作用和冗余性。在一场涵盖类风湿性关节炎、肿瘤学、淋巴细胞亚群、转录因子和非洲爪蟾中胚层等内容的讨论中,伦敦最近举行的一次会议探讨了细胞因子的最新进展。