Dawood M Y
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Medical School, Houston.
Int J Gynaecol Obstet. 1993;40 Suppl:S29-42.
The mechanisms of action of estrogen/progestin oral contraceptives, derivatives of testosterone including danazol and synthetic luteinizing hormone or gonadotropin-releasing hormone agonists in the treatment of endometriosis are reviewed. The selection of therapy depends on the stage of endometriosis, symptoms, current and future fertility needs, patient's age and recurrence rates. The efficacy, dosing regimens, effects on menstruation and fertility, recurrence rates and potential adverse effects, with particular emphasis on bone loss, of alternative therapies are compared.
本文综述了雌激素/孕激素口服避孕药、包括达那唑在内的睾酮衍生物以及合成促黄体生成素或促性腺激素释放激素激动剂在治疗子宫内膜异位症中的作用机制。治疗方法的选择取决于子宫内膜异位症的分期、症状、当前和未来的生育需求、患者年龄以及复发率。比较了替代疗法的疗效、给药方案、对月经和生育的影响、复发率以及潜在不良反应，尤其着重于骨质流失方面。
