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吐根碱肌病和心肌病。

Ipecac myopathy and cardiomyopathy.

作者信息

Dresser L P, Massey E W, Johnson E E, Bossen E

机构信息

Department of Medicine, Duke University Medical Center, Durham, NC 27710.

出版信息

J Neurol Neurosurg Psychiatry. 1993 May;56(5):560-2. doi: 10.1136/jnnp.56.5.560.

DOI:10.1136/jnnp.56.5.560
PMID:8099367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1015020/
Abstract

Two cases of ipecac myopathy, one with associated cardiomyopathy are reported. Both patients were young women with eating disorders who came to medical attention because of diffuse muscle weakness. Clinical and electromyographic data suggested ipecac myopathy and muscle biopsies confirmed this diagnosis. One patient had associated clinical and echocardiographic evidence of significant cardiomyopathy. The myopathy resolved and the echocardiogram returned to normal after discontinuing the use of ipecac.

摘要

报告了两例吐根碱肌病，其中一例伴有心肌病。两名患者均为患有饮食失调症的年轻女性，因弥漫性肌无力前来就医。临床和肌电图数据提示为吐根碱肌病，肌肉活检证实了这一诊断。一名患者有明显心肌病的临床和超声心动图证据。停用吐根碱后，肌病得到缓解，超声心动图恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9d4/1015020/a9d0429d4e96/jnnpsyc00478-0129-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9d4/1015020/397e7675a74c/jnnpsyc00478-0129-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9d4/1015020/a9d0429d4e96/jnnpsyc00478-0129-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9d4/1015020/397e7675a74c/jnnpsyc00478-0129-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9d4/1015020/a9d0429d4e96/jnnpsyc00478-0129-b.jpg

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2
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本文引用的文献

1
Fibre type changes in striated muscle of alcoholics.酗酒者横纹肌的纤维类型变化
J Clin Pathol. 1981 Sep;34(9):991-5. doi: 10.1136/jcp.34.9.991.
2
Emetine myopathy: two case reports with pathobiochemical analysis.
Muscle Nerve. 1984 Jan;7(1):54-9. doi: 10.1002/mus.880070109.
3
Ipecac-induced myopathy simulating dermatomyositis.吐根碱诱发的类似皮肌炎的肌病。
Neurology. 1982 Jan;32(1):91-4. doi: 10.1212/wnl.32.1.91.
J Eat Disord. 2023 Jan 30;11(1):13. doi: 10.1186/s40337-022-00724-5.
4
Application of emetine in SARS-CoV-2 treatment: regulation of p38 MAPK signaling pathway for preventing emetine-induced cardiac complications.盐酸依米丁在 SARS-CoV-2 治疗中的应用：调控 p38MAPK 信号通路预防盐酸依米丁诱导的心脏并发症。
Cell Cycle. 2022 Nov;21(22):2379-2386. doi: 10.1080/15384101.2022.2100575. Epub 2022 Jul 19.
5
The medical complications associated with purging.与清除相关的医学并发症。
Int J Eat Disord. 2016 Mar;49(3):249-59. doi: 10.1002/eat.22504. Epub 2016 Feb 15.
6
Toxic myopathies.中毒性肌病。
Neurol Clin. 2014 Aug;32(3):647-70, viii. doi: 10.1016/j.ncl.2014.04.009.
7
[Anesthesia in patients with anorexia nervosa and bulimia nervosa].[神经性厌食症和神经性贪食症患者的麻醉]
Anaesthesist. 2010 Mar;59(3):261-72; quiz 273. doi: 10.1007/s00101-009-1665-2.
8
Biotransformation of the ipecac alkaloids cephaeline and emetine from ipecac syrup in rats.吐根糖浆中吐根碱和依米丁这两种吐根生物碱在大鼠体内的生物转化。
Eur J Drug Metab Pharmacokinet. 2002 Jan-Mar;27(1):29-35. doi: 10.1007/BF03190402.
9
Absorption, distribution and excretion of 3H-labeled cephaeline- and emetine-spiked ipecac syrup in rats.大鼠体内3H标记的吐根碱和依米丁加标吐根糖浆的吸收、分布及排泄情况。
Eur J Drug Metab Pharmacokinet. 2002 Jan-Mar;27(1):17-27. doi: 10.1007/BF03190401.
10
Rapidly reversible cardiomyopathy associated with chronic ipecac ingestion.与长期服用吐根糖浆相关的快速可逆性心肌病。
Clin Cardiol. 1998 Oct;21(10):780-3. doi: 10.1002/clc.4960211018.
4
Death resulting from ipecac syrup poisoning.
JAMA. 1980 May 16;243(19):1927-8.
5
Ultrastructural pathology in emetine-induced myopathy.
Acta Neuropathol. 1988;75(6):577-82. doi: 10.1007/BF00686202.
6
A case of abuse of syrup of ipecac resulting in death.一例因滥用吐根糖浆导致死亡的病例。
J Am Coll Health. 1986 Jun;34(6):280-2. doi: 10.1080/07448481.1986.9938951.
7
The epidemiology of ipecac abuse.吐根碱滥用的流行病学。
N Engl J Med. 1986 Jan 23;314(4):245-6. doi: 10.1056/NEJM198601233140414.
8
Reversible ipecac myopathy.可复性吐根碱肌病
Arch Neurol. 1985 Feb;42(2):188-90. doi: 10.1001/archneur.1985.04060020106024.
9
Experimental (-) emetine myopathy. Ultrastructural and morphometric observations.实验性（-）吐根碱肌病。超微结构和形态测量观察。
J Neurol Sci. 1978 Nov;39(1):1-15. doi: 10.1016/0022-510x(78)90183-1.
10
Toxicology of ipecac: a review.
Clin Toxicol. 1977;10(2):221-42. doi: 10.3109/15563657708987968.