慢性髓性白血病急性期的11号染色体三体
Trisomy 11 in acute phase of chronic myeloid leukemia.
作者信息
Philip P E
出版信息
Acta Haematol. 1975;54(3):188-91. doi: 10.1159/000208071.
PMID:809963
Abstract
A female patient with chronic myeloid leukemia in acute phase was found to have trisomy 11 in her bone marrow cells. The contemporary existence of different clones suggests the following clonal evolution: 46,XX leads to 46,XX,Ph' leads to 47,XX,Ph', +11 leads to 48,XX,Ph', +11, +Ph'. It is suggested, that the cytogenetic events leading to trisomy C in advanced cases of chronic myeloid leukemia are of a different character than those which often results in trisomy C in other myeloid disorders.
摘要
一名处于急性期的慢性髓性白血病女性患者被发现其骨髓细胞中存在11号染色体三体。不同克隆的同时存在提示了以下克隆进化过程：46,XX导致46,XX,Ph'，进而导致47,XX,Ph', +11，再导致48,XX,Ph', +11, +Ph'。有人提出，在慢性髓性白血病晚期病例中导致C组染色体三体的细胞遗传学事件与在其他髓系疾病中常导致C组染色体三体的事件具有不同的性质。
相似文献
1
Trisomy 11 in acute phase of chronic myeloid leukemia.慢性髓性白血病急性期的11号染色体三体
Acta Haematol. 1975;54(3):188-91. doi: 10.1159/000208071.
2
[Karyotype in chronic myeloid leukemia in a blastic crisis. II. Trisomy 17].[慢性髓细胞白血病急变期的核型。II. 17三体]
Boll Soc Ital Biol Sper. 1981 Jan 30;57(2):149-51.
3
Chromosome changes in a patient achieving complete remission in the acute phase of chronic myelogenous leukemia.一名在慢性粒细胞白血病急性期达到完全缓解的患者的染色体变化
Am J Hematol. 1979;6(2):155-61. doi: 10.1002/ajh.2830060208.
4
Trisomy 11 in a patient with Ph-negative chronic myelogenous leukemia.11号染色体三体见于1例Ph阴性慢性髓性白血病患者。
Cancer Genet Cytogenet. 1986 Apr 15;21(4):343-5. doi: 10.1016/0165-4608(86)90215-3.
5
Two cases of trisomy 19 as a sole chromosomal abnormality in myeloid disorders.两例19号染色体三体作为髓系疾病中唯一的染色体异常情况。
Korean J Lab Med. 2008 Jun;28(3):174-8. doi: 10.3343/kjlm.2008.28.3.174.
6
Meaning of chromosome 6 aberrations in Ph'-positive chronic granulocytic leukemia.6号染色体畸变在Ph'阳性慢性粒细胞白血病中的意义。
Haematologica. 1984 Nov-Dec;69(6):661-70.
7
Trisomy 8 in bone marrow cells of patients with polycythemia vera and myelogenous leukemia.真性红细胞增多症和骨髓性白血病患者骨髓细胞中的8三体。
Clin Genet. 1974;6(4):258-64. doi: 10.1111/j.1399-0004.1974.tb02087.x.
8
[Chronic myeloid leukemia, Ph negative with chromosome 8 trisomy. A case report].[慢性髓性白血病，Ph阴性伴8号染色体三体。病例报告]
Acta Biomed Ateneo Parmense. 1982;53(4):243-7.
9
Trisomy D in bone marrow cells in a patient with chronic myelogenous leukemia.一名慢性粒细胞白血病患者骨髓细胞中的D三体。
Acta Haematol. 1974;52(1):61-4. doi: 10.1159/000208221.
10
Trisomy 22 in acute myeloid leukemia: a marker for myeloid leukemia with monocytic features and cytogenetically cryptic inversion 16.急性髓系白血病中的22号染色体三体：具有单核细胞特征的髓系白血病及细胞遗传学隐匿性16号染色体倒位的一个标志物
Cancer Genet Cytogenet. 1999 Mar;109(2):131-3. doi: 10.1016/s0165-4608(98)00145-9.
Zotero 插件