Okisaka S, Kuwabara T, Aiello L M
Am J Ophthalmol. 1975 Oct;80(4):591-601. doi: 10.1016/0002-9394(75)90389-x.
Using ruby and argon lasers, we produced multiple lesions on normal rhesus monkey retinas. The clinically used energy levels of both lasers produced identical cellular changes in the retina. Neither laser directly produced obliteration of capillaries. However, after the cellular damage in each burn lesion was repaired, we observed delayed degeneration of capillaries in a small segment at the burned areas. The marked reduction of active retinal cells that reduce vascular activity may beneficially affect laser treatment of diabetic retinopathy. The retinal tissue appears to have excessive photoreceptor cells and the horizontal connection of other cells seems to compensate for visual function after loss of many photoreceptor cells. We demonstrated severe damage in the ganglion cells by argon laser when it was aimed at the thick blood films in the vitreous cavity. Certain precautions must be taken when peripapillary neovascularization is treated by laser beam.
我们使用红宝石激光和氩激光在正常恒河猴视网膜上制造了多个损伤。两种激光的临床使用能量水平在视网膜上产生了相同的细胞变化。两种激光都没有直接导致毛细血管闭塞。然而，在每个烧灼损伤处的细胞损伤修复后，我们观察到烧灼区域一小段毛细血管的延迟退变。减少血管活性的活跃视网膜细胞的显著减少可能对糖尿病性视网膜病变的激光治疗产生有益影响。视网膜组织似乎有过多的光感受器细胞，并且在许多光感受器细胞丧失后，其他细胞的水平连接似乎可以补偿视觉功能。当氩激光瞄准玻璃体腔中的厚血膜时，我们证明了神经节细胞受到严重损伤。在用激光束治疗视盘周围新生血管时必须采取某些预防措施。
