溃疡性结肠炎患者和健康受试者血浆胃泌素、皮质醇和生长抑素水平的昼夜节律性及相互相关性
Circadian rhythmicity and cross correlation of plasma gastrin, cortisol and somatostatin levels in ulcerative colitis patients and healthy subjects.
作者信息
Payer J, Huorka M, Duris I, Mikulecký M, Kratochvíl'ová H, Ondrejka P
机构信息
1st Department of Internal Medicine, Comenius University, Bratislava, Czechoslovakia.
出版信息
Hepatogastroenterology. 1993 Jun;40(3):272-5.
PMID:8100796
Abstract
Gastrin, somatostatin and cortisol circadian (24 hours) rhythmicity was confirmed in healthy subjects. Gastrin and cortisol circadian rhythmicity was studied and also established in patients with ulcerative colitis (UC). UC patients were found to have a lower 24-hour amplitude of plasma cortisol and a shorter acrophase of plasma gastrin. Gastrin correlated positively with somatostatin and negatively with cortisol.
摘要
在健康受试者中证实了胃泌素、生长抑素和皮质醇的昼夜（24小时）节律性。对溃疡性结肠炎（UC）患者的胃泌素和皮质醇昼夜节律性进行了研究并得以确立。发现UC患者血浆皮质醇的24小时振幅较低，血浆胃泌素的峰值相位较短。胃泌素与生长抑素呈正相关，与皮质醇呈负相关。
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