Rosen J, Pollock B G, Altieri L P, Jonas E A
Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213.
Am J Psychiatry. 1993 Aug;150(8):1249-51. doi: 10.1176/ajp.150.8.1249.
A double-blind, placebo-controlled study of bethanechol was conducted in 26 elderly depressed patients being treated with nortriptyline. Patients receiving bethanechol had reduced subjective complaints of anticholinergic side effects and showed a trend toward improvement on an objective measure of salivary flow. The potential use of bethanechol in older patients to reduce morbidity and improve compliance with medication regimens is discussed.
