Kampman K, Brady J P
Department of Psychiatry, University of Pennsylvania, Philadelphia 19104.
J Clin Psychopharmacol. 1993 Aug;13(4):284-5.
A double-blind trial of bethanechol for the treatment of stuttering that used a crossover experimental design failed to find the drug superior to placebo. However, two of the patients who did respond favorably elected to continue with the medication and have remained more fluent after taking the drug for 6 months. The notion of "bethanechol responders" is advanced.
一项使用交叉实验设计的关于氨甲酰甲胆碱治疗口吃的双盲试验未能发现该药物优于安慰剂。然而，两名确实有良好反应的患者选择继续用药，在服用该药物6个月后说话变得更加流畅。文中提出了“氨甲酰甲胆碱反应者”这一概念。
