Santachiara Benerecetti A S, Semino O, Passarino G, Torroni A, Brdicka R, Fellous M, Modiano G
Dipartimento di Biologia Cellulare, Università della Calabria, Cosenza, Italy.
Ann Hum Genet. 1993 Jan;57(1):55-64. doi: 10.1111/j.1469-1809.1993.tb00886.x.
About 80 Sephardim, 80 Ashkenazim and 100 Czechoslovaks were examined for the Y-specific RFLPs revealed by the probes p12f2 and p49a,f on TaqI DNA digests. The aim of the study was to investigate the origin of the Ashkenazi gene pool through the analysis of markers which, having an exclusively holoandric transmission, are useful to estimate paternal gene flow. The comparison of the two groups of Jews with each other and with Czechoslovaks (which have been taken as a representative source of foreign Y-chromosomes for Ashkenazim) shows a great similarity between Sephardim and Ashkenazim who are very different from Czechoslovaks. On the other hand both groups of Jews appear to be closely related to Lebanese. A preliminary evaluation suggests that the contribution of foreign males to the Ashkenazi gene pool has been very low (1% or less per generation).
对约80名西班牙系犹太人、80名德系犹太人以及100名捷克斯洛伐克人进行了检测，以观察探针p12f2和p49a,f在TaqI酶切的DNA上所揭示的Y染色体特异性限制性片段长度多态性。本研究的目的是通过分析具有完全限雄遗传的标记来调查德系犹太人基因库的起源，这些标记有助于估计父系基因流动。将两组犹太人相互比较，并与捷克斯洛伐克人（被视为德系犹太人外来Y染色体的代表性来源）进行比较，结果显示西班牙系犹太人和德系犹太人之间有很大相似性，而他们与捷克斯洛伐克人则有很大差异。另一方面，两组犹太人似乎都与黎巴嫩人密切相关。初步评估表明，外来男性对德系犹太人基因库的贡献非常低（每代1%或更少）。
