英国萨默塞特郡人类汉坦病毒感染的临床谱
The clinical spectrum of human hantavirus infection in Somerset, UK.
作者信息
Pether J V, Lloyd G
机构信息
Public Health Laboratory, Musgrove Park Hospital, Taunton, Somerset, UK.
出版信息
Epidemiol Infect. 1993 Aug;111(1):171-5. doi: 10.1017/s095026880005679x.
Abstract
The signs and symptoms exhibited by 29 patients with an acute illness in whom antibodies to hantavirus were detected are described. In the severe cases the most striking signs and symptoms were the persistence for 2 or 3 weeks of a severe sore throat with pyrexia that developed early in the illness, followed by swelling of the face, neck and extremities, with arthropathy and prolonged malaise that lasted for months. A macular erythematous rash, hepatomegaly with abnormal liver function tests, and a tendency to haemorrhage was a later feature of the severe cases. Mild cases presented with a variety of signs and symptoms that were very difficult to link together as a syndrome.
摘要
本文描述了29例检测出汉坦病毒抗体的急性病患者所表现出的体征和症状。在严重病例中，最显著的体征和症状是在疾病早期出现伴有发热的严重咽痛，并持续2至3周，随后面部、颈部和四肢肿胀，伴有关节病和持续数月的长期不适。严重病例的后期特征是出现斑丘疹、肝功能检查异常的肝肿大以及出血倾向。轻症病例表现出各种体征和症状，很难将其作为一种综合征联系在一起。
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