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在野生捕获的新大陆灵长类动物中未检测到人类嗜T淋巴细胞病毒抗体。

Failure to detect human T-lymphotropic virus antibody in wild-caught New World primates.

作者信息

Kaplan J E, Holland M U, Green D B, Gracia F, Reeves W C

机构信息

Retrovirus Diseases Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.

出版信息

Am J Trop Med Hyg. 1993 Aug;49(2):236-8. doi: 10.4269/ajtmh.1993.49.236.

DOI:10.4269/ajtmh.1993.49.236
PMID:8102837
Abstract

We conducted a study to look for a simian counterpart of human T-lymphotropic virus (HTLV) in wild-caught monkeys in the Republic of Panama. Serum specimens were obtained from 102 monkeys (Ateles fusciceps, n = 75; Alouatta villosa, n = 18; and Cebus capucinus, n = 9) captured in Panama's Darien rain forest in 1979-1980. Specimens were screened for HTLV antibody by enzyme-linked immunosorbent assay, and reactive specimens were further tested by Western blot. None of the 102 specimens were seropositive for HTLV. Our findings provide no evidence for an HTLV-like virus in New World primates from Panama, but the sample size was small, and further studies are warranted.

摘要

我们开展了一项研究,旨在寻找巴拿马共和国野生捕获猴子中人类嗜T淋巴细胞病毒(HTLV)的猿类对应物。血清标本取自1979 - 1980年在巴拿马达连雨林捕获的102只猴子(黑掌蛛猴,n = 75;绒毛蛛猴,n = 18;白喉卷尾猴,n = 9)。通过酶联免疫吸附测定法对标本进行HTLV抗体筛查,反应性标本进一步用蛋白质印迹法检测。102份标本中无一例HTLV血清学阳性。我们的研究结果未提供巴拿马新大陆灵长类动物中存在类HTLV病毒的证据,但样本量较小,有必要进行进一步研究。

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引用本文的文献

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