Chakrabarty A N, Bhattacharya C P, Dastidar S G
Department of Medical Microbiology and Parasitology, Calcutta University College of Medicine, India.
APMIS. 1993 Jun;101(6):449-54. doi: 10.1111/j.1699-0463.1993.tb00133.x.
Methdilazine (Md) could inhibit various Mycobacterium spp. at 5-15 micrograms/ml concentrations in vitro as well as in vivo. When Md was tested in combination with streptomycin (Sm), rifampicin (Rf) or methyl-DOPA (m-D), it showed synergistic effects only with respect to methyl-DOPA.
甲硫哒嗪(Md)在体外和体内均可在5-15微克/毫升的浓度下抑制各种分枝杆菌属。当甲硫哒嗪与链霉素(Sm)、利福平(Rf)或甲基多巴(m-D)联合测试时,它仅对甲基多巴显示出协同作用。