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抗微生物吩噻嗪类药物甲哌氯丙嗪（Md）的抗分枝杆菌活性

Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine.

作者信息

Chakrabarty A N, Bhattacharya C P, Dastidar S G

机构信息

Department of Medical Microbiology and Parasitology, Calcutta University College of Medicine, India.

出版信息

APMIS. 1993 Jun;101(6):449-54. doi: 10.1111/j.1699-0463.1993.tb00133.x.

DOI:10.1111/j.1699-0463.1993.tb00133.x
PMID:8103345
Abstract

Methdilazine (Md) could inhibit various Mycobacterium spp. at 5-15 micrograms/ml concentrations in vitro as well as in vivo. When Md was tested in combination with streptomycin (Sm), rifampicin (Rf) or methyl-DOPA (m-D), it showed synergistic effects only with respect to methyl-DOPA.

摘要

甲硫哒嗪（Md）在体外和体内均可在5-15微克/毫升的浓度下抑制各种分枝杆菌属。当甲硫哒嗪与链霉素（Sm）、利福平（Rf）或甲基多巴（m-D）联合测试时，它仅对甲基多巴显示出协同作用。

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Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine.抗微生物吩噻嗪类药物甲哌氯丙嗪（Md）的抗分枝杆菌活性
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