Senanayake N, de Silva H J, Karalliedde L
Department of Medicine, Faculty of Medicine, University of Peradeniya, Sri Lanka.
Hum Exp Toxicol. 1993 Jul;12(4):297-9. doi: 10.1177/096032719301200407.
We have developed a clinical scale to assess severity or organophosphorus (OP) intoxication. Five common clinical manifestations of OP poisoning have been selected as parameters, each to be assessed on a 3 point scale varying from 0-2. Poisoning can then be graded as mild (score 0-3), moderate (score 4-7) or severe (score 8-11) when the patient first presents. The scale was validated using two consecutive series of 173 patients with OP poisoning. Correlations between the scores obtained on admission and three outcome variables, namely, death, the need for ventilatory support and the dose of atropine required in the first 24 hours after admission were significant. We believe that this scale would assist in grading severity of OP intoxication at first contact and help in predicting possible outcome.
我们已经开发出一种临床量表来评估有机磷（OP）中毒的严重程度。选取了OP中毒的五种常见临床表现作为参数，每种表现按0至2分的三分制进行评估。当患者首次就诊时，中毒可分为轻度（得分0至3分）、中度（得分4至7分）或重度（得分8至11分）。该量表通过连续两组共173例OP中毒患者进行了验证。入院时获得的分数与三个结局变量之间的相关性显著，这三个结局变量分别是死亡、是否需要通气支持以及入院后首24小时所需阿托品的剂量。我们认为，该量表将有助于在初次接触时对OP中毒的严重程度进行分级，并有助于预测可能的结局。
