Levy F
Avoca Clinic, Prince of Wales Children's Hospital, Randwick, New South Wales, Australia.
J Paediatr Child Health. 1993 Aug;29(4):250-4. doi: 10.1111/j.1440-1754.1993.tb00504.x.
The current literature on side effects of central nervous system (CNS) stimulant medications used in the treatment of attention deficit hyperactivity disorder (ADHD) is reviewed, with particular emphasis on dose-response effects on differing behavioural systems. The reasons for variation in findings may lie in individual differences in children, or in differing responses of target behavioural systems. These may be understood in terms of underlying pharmacological mechanisms. Social, educational and philosophical issues relating to medication use are discussed, and the need for ongoing critical clinical and research approaches, rather than polarization of professional attitudes, is emphasized.
本文综述了目前关于用于治疗注意力缺陷多动障碍（ADHD）的中枢神经系统（CNS）兴奋药物副作用的文献，特别强调了对不同行为系统的剂量反应效应。研究结果存在差异的原因可能在于儿童个体差异，或目标行为系统的不同反应。这可以从潜在的药理学机制方面来理解。文中讨论了与药物使用相关的社会、教育和哲学问题，并强调需要持续采用严谨的临床和研究方法，而非使专业态度两极分化。
