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人类免疫缺陷病毒感染中可溶性CD54(细胞间黏附分子-1)水平升高。

Elevated levels of soluble CD54 (ICAM-1) in human immunodeficiency virus infection.

作者信息

Reddy M M, Grieco M H

机构信息

R.A. Cooke Institute of Allergy, St. Luke's-Roosevelt Hospital Center, New York, New York 10019.

出版信息

J Clin Lab Anal. 1993;7(5):269-72. doi: 10.1002/jcla.1860070506.

DOI:10.1002/jcla.1860070506
PMID:8105044
Abstract

Soluble CD54 levels in sera were quantitated in asymptomatic intravenous drug users, homosexuals, and patients with lymphadenopathy, AIDS-related complex, or acquired immunodeficiency syndrome. Soluble CD54 levels were elevated in human immunodeficiency virus (HIV)-seronegative asymptomatic intravenous drug users, reflecting infections like cytomegalovirus, Epstein-Barr virus, and hepatitis B virus. The sera of human immunodeficiency virus-seropositive groups of patients also had elevated levels of soluble CD54, reflecting infections like cytomegalovirus and human immunodeficiency virus infection.

摘要

对无症状静脉吸毒者、同性恋者以及患有淋巴结病、艾滋病相关综合征或获得性免疫缺陷综合征的患者血清中的可溶性CD54水平进行了定量检测。在人类免疫缺陷病毒(HIV)血清阴性的无症状静脉吸毒者中,可溶性CD54水平升高,这反映了巨细胞病毒、EB病毒和乙型肝炎病毒等感染。人类免疫缺陷病毒血清阳性患者组的血清中可溶性CD54水平也升高,这反映了巨细胞病毒感染和人类免疫缺陷病毒感染。

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