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人类免疫缺陷病毒感染人群血清中可溶性CD8水平升高。

Elevated soluble CD8 levels in sera of human immunodeficiency virus-infected populations.

作者信息

Reddy M M, Lange M, Grieco M H

机构信息

R. A. Cooke Institute of Allergy, St. Luke's-Roosevelt Hospital Center, New York, New York 10019.

出版信息

J Clin Microbiol. 1989 Feb;27(2):257-60. doi: 10.1128/jcm.27.2.257-260.1989.

DOI:10.1128/jcm.27.2.257-260.1989
PMID:2492539
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC267287/
Abstract

Soluble CD8 levels in sera were quantitated in asymptomatic intravenous drug abusers, homosexuals, and patients with lymphadenopathy or acquired immunodeficiency syndrome. Soluble CD8 levels were elevated in human immunodeficiency virus-seronegative intravenous drug abusers and homosexuals, probably reflecting infections like cytomegalovirus. The sera of human immunodeficiency virus-seropositive groups of patients with human immunodeficiency virus infection also had elevated levels of soluble CD8, reflecting infections like cytomegalovirus and human immunodeficiency virus infection.

摘要

对无症状静脉注射吸毒者、同性恋者以及患有淋巴结病或获得性免疫缺陷综合征的患者血清中的可溶性CD8水平进行了定量分析。在人类免疫缺陷病毒血清阴性的静脉注射吸毒者和同性恋者中,可溶性CD8水平升高,这可能反映了巨细胞病毒等感染。人类免疫缺陷病毒感染的人类免疫缺陷病毒血清阳性患者组的血清中可溶性CD8水平也升高,这反映了巨细胞病毒感染和人类免疫缺陷病毒感染。

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本文引用的文献

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Acid-labile human leukocyte interferon in homosexual men with Kaposi's sarcoma and lymphadenopathy.患有卡波西肉瘤和淋巴结病的同性恋男性体内的酸不稳定型人白细胞干扰素
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The role of T cell differentiation markers in antigen-specific and lectin-dependent cellular cytotoxicity mediated by T8+ and T4+ human cytotoxic T cell clones directed at class I and class II MHC antigens.T细胞分化标志物在由针对I类和II类MHC抗原的T8 +和T4 +人细胞毒性T细胞克隆介导的抗原特异性和凝集素依赖性细胞毒性中的作用。
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