Gualtieri C T
North Carolina Neuropsychiatry Clinic.
Brain Cogn. 1993 Sep;23(1):102-9. doi: 10.1006/brcg.1993.1048.
Akathisia is a disorder characterized by restlessness and dysphoria. Neuroleptic-induced akathisia is one of the acute extrapyramidal reactions caused by neuroleptic drugs, and tardive akathisia (TDAK) is a tardive dyskinesia (TD) variant caused by long-term neuroleptic treatment. Since TDAK is a movement disorder with a psychological dimension, it merits consideration as one of the behavioral variants of TD. TDAK is considered in light of an ongoing, prospective study in mentally retarded people. It is discussed in terms of the "cognitive" functions of the basal ganglia, and the known consequences of other diseases of the basal ganglia that almost invariably cause behavioral and cognitive deterioration.
静坐不能是一种以坐立不安和烦躁不安为特征的病症。抗精神病药物所致静坐不能是抗精神病药物引起的急性锥体外系反应之一，迟发性静坐不能（TDAK）是长期使用抗精神病药物治疗所致的迟发性运动障碍（TD）变体。由于TDAK是一种具有心理维度的运动障碍，它值得被视为TD的行为变体之一。根据一项针对智障人士的正在进行的前瞻性研究来考虑TDAK。从基底神经节的“认知”功能以及基底神经节其他疾病几乎总是导致行为和认知恶化的已知后果方面进行了讨论。
