Smith N N, Harvey W F, Bedford J S, Coss R A
Department of Radiation Oncology and Nuclear Medicine, Jefferson Cancer Institute, Thomas Jefferson University, Philadelphia, PA 19107.
Int J Hyperthermia. 1993 Nov-Dec;9(6):799-802. doi: 10.3109/02656739309034982.
This study examines the differential heat sensitivity of rounded suspension cells versus flattened monolayer cells. G1 populations of two different Chinese hamster ovary lines were used to eliminate possible cell cycle artifacts. The cell populations were heated at 43 and 45 degrees C. In all cases, cells treated in suspension were less sensitive to heat killing than cells treated as monolayers.
本研究考察了圆形悬浮细胞与扁平单层细胞对热敏感性的差异。使用两种不同的中国仓鼠卵巢细胞系的G1期细胞群体以消除可能的细胞周期假象。将细胞群体在43℃和45℃下加热。在所有情况下，悬浮处理的细胞比单层处理的细胞对热杀伤更不敏感。
