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糖尿病昏迷胰岛素治疗的新进展(作者译)

[New developments in insulin therapy of diabetic coma (author's transl)].

作者信息

Dennin D E

出版信息

MMW Munch Med Wochenschr. 1975 Oct 10;117(41):1667-70.

PMID:810692
Abstract

The experiences of English teams with continuous intravenous infusion of small doses of insulin (6-10 IU/h) for the treatment of diabetic ketoacidosis are reported. This form of therapy is based on recent knowledge of the physiological degree of the serum insulin level (20-200 muU/ml) and the quantity required to saturate the insulin receptors. The advantages of this treatment are in the low therapeutic risk: hypopotassemia, hypoglycemia and cerebral edema, which are disadvantages of conventional therapy of diabetic coma, are avoided.

摘要

据报道,英国团队采用持续静脉输注小剂量胰岛素(6 - 10国际单位/小时)治疗糖尿病酮症酸中毒的经验。这种治疗方式基于近期对血清胰岛素水平生理程度(20 - 200微单位/毫升)以及使胰岛素受体饱和所需剂量的认识。这种治疗方法的优点是治疗风险低:避免了低钾血症、低血糖和脑水肿,而这些是糖尿病昏迷传统治疗方法的缺点。

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