Franssen H, Wieneke G H
Rudolf Magnus Research School in the Neurosciences, Department of Clinical Neurophysiology, Utrecht, The Netherlands.
Muscle Nerve. 1994 Mar;17(3):336-44. doi: 10.1002/mus.880170313.
The purpose of this study was to estimate the time needed to warm an extremity prior to measuring nerve conduction. In 8 normal subjects tibial and sural nerve conduction variables were measured during cooling and warming of the leg in water of 18 degrees C and 36 degrees C, respectively. During cooling, nerve conduction velocity (NCV) decreased and distal motor latency (DML), duration, and area of the compound muscle action potentials (CMAP), and compound nerve action potentials (CNAP) increased. The reverse occurred during warming. During cooling or warming the change in these variables became progressively smaller with time. The time course could therefore be described by an exponential relation, the parameters of which were determined. On the basis of these data, correlations were calculated between the skin temperature at the start of the investigation and the warming time needed to obtain a good estimate of nerve conduction variables at 36 degrees C. The use of correction factors, instead of actual warming, yielded acceptable errors only for NCV and not for the other variables.
本研究的目的是估计在测量神经传导之前使肢体变暖所需的时间。在8名正常受试者中，分别在18摄氏度和36摄氏度的水中对腿部进行冷却和加热时，测量胫神经和腓肠神经传导变量。在冷却过程中，神经传导速度（NCV）降低，复合肌肉动作电位（CMAP）和复合神经动作电位（CNAP）的远端运动潜伏期（DML）、持续时间和面积增加。在加热过程中则出现相反情况。在冷却或加热过程中，这些变量随时间的变化逐渐变小。因此，时间进程可用指数关系来描述，并确定了其参数。基于这些数据，计算了研究开始时的皮肤温度与在36摄氏度下获得神经传导变量良好估计所需的加热时间之间的相关性。使用校正因子而非实际加热，仅对NCV产生了可接受的误差，而对其他变量则不然。
