Romaniuk J R, Celichowski J, Kowalski K
Department of Neurophysiology, Polish Academy of Sciences, Warsaw.
Acta Neurobiol Exp (Wars). 1993;53(4):557-61.
Phrenic and external intercostal motor responses to inspiratory load were studied in anaesthetized rabbits and after bilateral vagotomy. Animals were ventilated with a phrenic nerve driven respirator set at different gains, i.e. volume to phrenic-signal ratio. Load was imposed by occluding the trachea at the end of expiration for the period of one breath. It was found that vagally mediated low threshold facilitation may be observed in rabbits on late-inspiratory external intercostal motor units. After vagotomy, external intercostal EMG response to load depended on the given of the servorespirator set during the period of assisted ventilation.
在麻醉兔及双侧迷走神经切断术后，研究了膈神经和肋间外肌运动对吸气负荷的反应。用设置了不同增益（即容积与膈神经信号比值）的膈神经驱动呼吸器对动物进行通气。在呼气末堵塞气管持续一个呼吸周期来施加负荷。结果发现，在兔的吸气后期肋间外肌运动单位上可观察到迷走神经介导的低阈值易化作用。迷走神经切断术后，肋间外肌肌电图对负荷的反应取决于辅助通气期间伺服呼吸器的设置。
