MGH-1、YOU-1和YOU-2超广谱β-内酰胺酶基因序列。
Sequences of MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamase genes.
作者信息
Rice L B, Marshall S H, Carias L L, Sutton L, Jacoby G A
机构信息
Department of Veterans Affairs Medical Center, Cleveland, Ohio.
出版信息
Antimicrob Agents Chemother. 1993 Dec;37(12):2760-1. doi: 10.1128/AAC.37.12.2760.
Abstract
Genes for MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamases have been cloned and sequenced. The gene for MGH-1 has the sequence of blaTEM-10, YOU-2 has that of blaTEM-12, and YOU-1 has that of blaTEM-26. All have evolved from blaTEM-1b but have the strong dual promoter sequence of blaTEM-2.
摘要
编码MGH-1、YOU-1和YOU-2超广谱β-内酰胺酶的基因已被克隆和测序。MGH-1基因具有blaTEM-10的序列，YOU-2基因具有blaTEM-12的序列，而YOU-1基因具有blaTEM-26的序列。所有这些基因均由blaTEM-1b进化而来，但都具有blaTEM-2的强双启动子序列。
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