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通过全身计数和59Fe的红细胞掺入法测定正常铁吸收。

Normal iron absorption determined by means of whole body counting and red cell incorporation of 59Fe.

作者信息

Larsen L, Milman N

出版信息

Acta Med Scand. 1975 Oct;198(4):271-4. doi: 10.1111/j.0954-6820.1975.tb19539.x.

DOI:10.1111/j.0954-6820.1975.tb19539.x
PMID:811086
Abstract

Gastrointestinal iron absorption has been measured in 27 apparently healthy subjects (8 males and 19 females) by means of whole body counting. Whole body retention 14 days after oral administration of 10 muCi59Fe with a carrier dose of 9.9 mg Fe2+ was used as an expression of absorption. The percentage incorporation of the orally applied 59Fe into the total erythrocyte mass within 14 days (erythrocyte incorporation) was estimated as well. Geometric mean iron absorption was 9.1 +/- 2.2 (S.D.) % in males and 8.3 +/- 2.1% in females; in the entire series it was 8.5 +/- 2.1%. The difference between males and females was not significant. Arithmetic mean red cell utilization of absorbed 59Fe was 92.9 +/- 4.0 (S.E.M.) % in the entire series. The correlation between iron absorption and erythrocyte incorporation was found to be highly significant (r=0.96, p less than 0.001).

摘要

通过全身计数法对27名表面健康的受试者(8名男性和19名女性)的胃肠道铁吸收情况进行了测量。口服10微居里59铁并伴有9.9毫克亚铁离子载体剂量后14天的全身铁潴留量被用作吸收情况的一种表达指标。同时还估算了口服的59铁在14天内整合到总红细胞量中的百分比(红细胞整合率)。男性的几何平均铁吸收率为9.1±2.2(标准差)%,女性为8.3±2.1%;在整个系列中为8.5±2.1%。男性和女性之间的差异不显著。在整个系列中,吸收的59铁的算术平均红细胞利用率为92.9±4.0(标准误)%。发现铁吸收与红细胞整合率之间的相关性非常显著(r = 0.96,p < 0.001)。

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