老年患者中的甲状腺激素：“T4 正常甲状腺功能”
Thyroid hormones in the elderly sick: "T4 euthyroidism".
作者信息
Burrows A W, Shakespear R A, Hesch R D, Cooper E, Aickin C M, Burke C W
出版信息
Br Med J. 1975 Nov 22;4(5994):437-9. doi: 10.1136/bmj.4.5994.437.
Abstract
Thyroid function and serum levels of triiodothyronine (T3) and thyroxine (T4) were investigated in 79 euthyroid geriatric patients. Of the 59 inpatients and 20 outpatients 35 (59%) and 2, respectively, had low T3 levels. In contrast, 7 (12%) and 6 (30%), respectively, had raised T4 levels. Two further patients were excluded from the study because of raised levels of thyroid-stimulating hormone. Thyroxine-binding globulin was greatly increased in both groups of patients, but low serum albumin levels were present in 31 (39%). Despite these changes free T3 and T4 indices closely followed total T3 and T4 levels. The difference between the two groups of patients did not correlate with body weight, diagnostic categories, age, drug treatment, or duration of stay in hospital.
摘要
对79例甲状腺功能正常的老年患者的甲状腺功能以及血清三碘甲状腺原氨酸（T3）和甲状腺素（T4）水平进行了研究。在59例住院患者和20例门诊患者中，分别有35例（59%）和2例T3水平较低。相比之下，分别有7例（12%）和6例（30%）T4水平升高。另有2例患者因促甲状腺激素水平升高而被排除在研究之外。两组患者的甲状腺素结合球蛋白均大幅升高，但31例（39%）患者血清白蛋白水平较低。尽管有这些变化，但游离T3和T4指数与总T3和T4水平密切相关。两组患者之间的差异与体重、诊断类别、年龄、药物治疗或住院时间无关。
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