Brogden R N, Pinder R M, Sawyer P R, Speight T M, Avery G S
Drugs. 1975;10(3):211-7. doi: 10.2165/00003495-197510030-00003.
At doses similar to those used in the treatment of chronic bronchial asthma, intranasal beclomethasone dipropionate is effective in alleviating nasal symptoms of seasonal allergic and perennial rhinitis in about three-quarters of patients. Eye symptoms are not relieved. The carry-over effect of the evening dose is useful in preventing early morning attacks of sneezing. Intranasal beclomethasone dipropionate is useful in controlling symptoms persisting after polypectomy and may possibly delay or eliminate the need for the surgical removal of nasal polyps, which may shrink after several weeks or months of treatment.
在与用于治疗慢性支气管哮喘的剂量相似的情况下,鼻内使用二丙酸倍氯米松可使约四分之三的季节性变应性和常年性鼻炎患者的鼻部症状得到缓解。眼部症状无法缓解。夜间剂量的持续作用有助于预防清晨打喷嚏发作。鼻内使用二丙酸倍氯米松有助于控制息肉切除术后持续存在的症状,并且可能延迟或消除手术切除鼻息肉的必要性,鼻息肉在治疗数周或数月后可能会缩小。