Mitchell S E, Anderson J H, Swindle M M, Strandberg J D, Kan J
Russell H. Morgan Department of Radiology and Radiologic Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Pediatr Cardiol. 1994 Jan-Feb;15(1):1-7. doi: 10.1007/BF00796998.
A new approach to creating an interatrial communication using a stationary fixed-diameter angioplasty balloon is presented. Stationary balloon septostomy was used to create an atrial communication in 19 young swine using a transseptal technique through a closed atrial septum, and in 18 newborn lambs through a patent foramen ovale. In animals with an intact septum, there was persistent patency of the atrial communication using balloons larger than 12 mm in diameter. The average diameter of the atrial communication was 96% of the expanded diameter of the angioplasty balloon. For newborn lambs with a patent foramen, a smooth oval atrial communication was noted by 4 weeks, and there was persistent patency of the opening using balloons larger than 15 mm in diameter. The average diameter of the opening was 81% of the diameter of the angioplasty balloon used. The new procedure was used successfully in five patients. All five showed resolution of the clinical symptomology. In conclusion, stationary angioplasty balloon atrial septostomy has been effective in producing interatrial communications, which remained patent for 4-14 weeks, in animals with intact septum, as well as in those with a patent foramen ovale.
介绍了一种使用固定直径血管成形术球囊创建房间隔交通的新方法。使用固定球囊房间隔造口术，通过经闭合房间隔的经房间隔技术，在19只幼年猪中创建房间隔交通；并通过卵圆孔未闭，在18只新生羔羊中创建房间隔交通。在房间隔完整的动物中，使用直径大于12mm的球囊时，房间隔交通持续通畅。房间隔交通的平均直径为血管成形术球囊扩张直径的96%。对于卵圆孔未闭的新生羔羊，4周时可见光滑的椭圆形房间隔交通，使用直径大于15mm的球囊时开口持续通畅。开口的平均直径为所用血管成形术球囊直径的81%。该新方法在5例患者中成功应用。所有5例患者的临床症状均得到缓解。总之，固定血管成形术球囊房间隔造口术在完整房间隔的动物以及卵圆孔未闭的动物中，有效产生了持续4至14周通畅的房间隔交通。
