同种异体移植细胞毒性。携带补体受体的T淋巴细胞的作用。
Allograft cytotoxicity. Role of T lymphocytes bearing a receptor for complement.
作者信息
Arnaiz-Villena A, Jones B, Roitt I M
出版信息
Immunology. 1975 Nov;29(5):903-8.
Abstract
The ability of sensitized spleen populations to kill allogenic mouse cells in vitro is lost after depletion of cells bearing receptors for C3. It is suggested that complement receptor T lymphocytes (T-CRL) play a role in the effector phase of specific cell-mediated cytotoxicity. The finding of large C3 rosette-forming cells staining for a specific T marker further supports the view that activated T cells may bear C3 receptors.
摘要
在去除带有C3受体的细胞后，致敏脾细胞群体在体外杀伤同种异体小鼠细胞的能力丧失。这表明补体受体T淋巴细胞（T-CRL）在特异性细胞介导的细胞毒性效应阶段发挥作用。大量C3花环形成细胞对特定T标记染色的发现进一步支持了活化T细胞可能带有C3受体的观点。
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