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阿尔茨海默型痴呆中的失读症。

Alexia in dementia of the Alzheimer's type.

作者信息

Arsland D, Larsen J P, Høien T

机构信息

Department of Psychiatry, Central Hospital of Rogaland, Stavanger, Norway.

出版信息

Acta Neurol Scand. 1993 Dec;88(6):434-9. doi: 10.1111/j.1600-0404.1993.tb05374.x.

DOI:10.1111/j.1600-0404.1993.tb05374.x
PMID:8116346
Abstract

The reading aloud of single words in 16 subjects with dementia of the Alzheimer's type (DAT) was compared with the performance of control subjects. The assessment included a computerised test-battery designed to assess word recognition ability and the efficiency of the two underlying reading strategies; the lexical and the non-lexical strategy. The DAT patients had severe difficulties in word recognition ability. Both accuracy score and reaction time were significantly impaired compared with the results in the control group. Furthermore, the results demonstrated that both the lexical and the non-lexical reading strategies were impaired. There was a significant correlation between reading performance and severity of dementia. However, no significant association between reading performance and age of onset or family history of dementia could be observed.

摘要

对16名阿尔茨海默病型痴呆(DAT)患者的单字朗读情况与对照组受试者的表现进行了比较。评估包括一个计算机化测试组,旨在评估单词识别能力以及两种基本阅读策略(词汇策略和非词汇策略)的效率。DAT患者在单词识别能力方面存在严重困难。与对照组结果相比,准确率得分和反应时间均显著受损。此外,结果表明词汇和非词汇阅读策略均受损。阅读表现与痴呆严重程度之间存在显著相关性。然而,未观察到阅读表现与发病年龄或痴呆家族史之间存在显著关联。

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Differential diagnosis of the major progressive dementias and depression in middle and late adulthood: a summary of the literature of the early 1990s.成年中晚期主要进行性痴呆与抑郁症的鉴别诊断:20世纪90年代初文献综述
Neuropsychol Rev. 1998 Sep;8(3):109-67. doi: 10.1023/a:1025628925796.